Cranial nerves

Cranial nerves


The table below lists the major characteristics of the 12 cranial nerves:

NerveFunctionsClinicalPathway/foramen
I (Olfactory)SmellCribriform plate
II (Optic)SightOptic canal
III (Oculomotor)Eye movement (MR, IO, SR, IR)
Pupil constriction
Accomodation
Eyelid opening
Palsy results in
  • ptosis
  • 'down and out' eye
  • dilated, fixed pupil
Superior orbital fissure (SOF)
IV (Trochlear)Eye movement (SO)Palsy results in defective downward gaze → vertical diplopiaSOF
V (Trigeminal)Facial sensation
Mastication
Lesions may cause:
  • trigeminal neuralgia
  • loss of corneal reflex (afferent)
  • loss of facial sensation
  • paralysis of mastication muscles
  • deviation of jaw to weak side
V1: SOF, V2: Foramen rotundum,
V3: Foramen ovale
VI (Abducens)Eye movement (LR)Palsy results in defective abduction → horizontal diplopiaSOF
VII (Facial)Facial movement
Taste (anterior 2/3rds of tongue)
Lacrimation
Salivation
Lesions may result in:
  • flaccid paralysis of upper + lower face
  • loss of corneal reflex (efferent)
  • loss of taste
  • hyperacusis
Internal auditory meatus
VIII (Vestibulocochlear)Hearing, balanceHearing loss
Vertigo, nystagmus
Acoustic neuromas are Schwann cell tumours of the cochlear nerve
Internal auditory meatus
IX (Glossopharyngeal)Taste (posterior 1/3rd of tongue)
Salivation
Swallowing
Mediates input from carotid body & sinus
Lesions may result in;
  • hypersensitive carotid sinus reflex
  • loss of gag reflex (afferent)
Jugular foramen
X (Vagus)Phonation
Swallowing
Innervates viscera
Lesions may result in;
  • uvula deviates away from site of lesion
  • loss of gag reflex (efferent)
Jugular foramen
XI (Accessory)Head and shoulder movementLesions may result in;
  • weakness turning head to contralateral side
Jugular foramen
XII (Hypoglossal)Tongue movementTongue deviates towards side of lesionHypoglossal canal

Some cranial nerves are motor, some sensory and some are both. The most useful mnemonic is given below.

CN I ----------------------------------------------------------------------→XII

Some Say Marry Money But MBrother Says Big Brains Matter Most

S = Sensory, M = Motor, B = Both


Image sourced from Wikipedia
View from the inferior surface of the brain showing the emergence of the cranial nerves

Image sourced from Wikipedia
Diagram showing the nuclei of the cranial nerves in the brainstem


Cranial nerve reflexes

ReflexAfferent limbEfferent limb
CornealOphthalmic nerve (V1)Facial nerve (VII)
Jaw jerkMandibular nerve (V3)Mandibular nerve (V3)
GagGlossopharyngeal nerve (IX)Vagal nerve (X)
Carotid sinusGlossopharyngeal nerve (IX)Vagal nerve (X)
Pupillary lightOptic nerve (II)Oculomotor nerve (III)
LacrimationOphthalmic nerve (V1)Facial nerve (VII)