Idiopathic intracranial hypertension

Idiopathic intracranial hypertension


Idiopathic intracranial hypertension (also known as pseudotumour cerebri and formerly benign intracranial hypertension) is a condition classically seen in young, overweight females.

Features
  • headache
  • blurred vision
  • papilloedema (usually present)
  • enlarged blind spot
  • sixth nerve palsy may be present

Risk factors
  • obesity
  • female sex
  • pregnancy
  • drugs*: oral contraceptive pill, steroids, tetracycline, vitamin A, lithium

Management
  • weight loss
  • diuretics e.g. acetazolamide
  • topiramate is also used, and has the added benefit of causing weight loss in most patients
  • repeated lumbar puncture
  • surgery: optic nerve sheath decompression and fenestration may be needed to prevent damage to the optic nerve. A lumboperitoneal or ventriculoperitoneal shunt may also be performed to reduce intracranial pressure

*if intracranial hypertension is thought to occur secondary to a known causes (e.g. Medication) then it is of course not idiopathic