Mock 131

Theme: Antipsychotic classification

A.Phenothiazine (Aliphatic side chain)
B.Thioxanthene
C.Butyrophenone
D.Dibenzodiazepine
E.Dibenzothiazepine
F.Diphenylbutylpiperidine
G.Phenothiazine (Piperizine side chain)
H.Benzoxasole
I.Thienobenzodiazepine
J.Substituted benzamide


Select the class of antipsychotic to which each of the following belong

NaN.Olanzapine

The correct answer is: Thienobenzodiazepine 62%



NaN.Chlorpromazine
 Phenothiazine (Aliphatic side chain) 75%



NaN.Clozapine
 Dibenzodiazepine 76%



Antipsychotics (classification)


Antipsychotics can be divided in a variety of ways. The most common way is to divide them into typical (first generation) and atypical types (second generation) (see table below).

Typical antipsychoticsAtypical antipsychotics
ChlorpromazineClozapine
FlupenthixolRisperidone
ZuclopenthixolOlanzapine
PerphenazineQuetiapine
TrifluoperazineZiprasidone
SulprideAmisulpride
HaloperidolAripiprazole

The other way they are classified is by structure. This is a favoured method by the royal college and they seem to like asking questions on this (see table below).

Antipsychotic classExamples
Phenothiazines (Aliphatic side chain)Chlorpromazine
Phenothiazines (Piperidine side chain)Thioridazine, pipothiazine
Phenothiazines (Piperizine side chain)Trifluoperazine, fluphenazine
ButyrophenonesHaloperidol
ThioxanthenesFlupenthixol, zuclupenthixol
DiphenylbutylpiperidinesPimozide
DibenzodiazepinesClozapine
BenzoxasolesRisperidone
ThienobenzodiazepinesOlanzapine
DibenzothiazepinesQuetiapine
Substituted benzamidesSulpride, amisulpride
Arylpiperidylindole (quinolone)Aripiprazole