Theme: Licensed indications for antidepressants
In each scenario, select the antidepressant with a licensed indication for the issue described
| A. | Citalopram |
| B. | Fluoxetine |
| C. | Paroxetine |
| D. | Imipramine |
| E. | Venlafaxine |
| F. | Amitriptyline |
| G. | Clomipramine |
| H. | Fluvoxamine |
| I. | Moclobemide |
| J. | Escitalopram |
In each scenario, select the antidepressant with a licensed indication for the issue described
| NaN. | A 19 year old man is brought to clinic by his mother who is concerned about his eating habits. He reports consuming large amounts of food over short time periods and then inducing vomiting. He also reports laxative abuse. He appears of normal weight. |
| The correct answer is: Fluoxetine 80% This is a clear description of bulimia nervosa (purging type). |
| NaN. | A young woman with narcolepsy is referred due to episodes of weakness. She describes occasions whereby her knees buckle when she gets excited by laugher or anger. |
| The correct answer is: Clomipramine 46% The muscle weakness is a description of cataplexy. Clomipramine has a license for this. |
| NaN. | An elderly woman is referred by her GP due to being unable to return to her home since she was burgled. She has been staying with her daughter since the incident whereby two men entered her house and robbed her at gun point. She describes flashbacks and nightmares and is easily startled. |
| The correct answer is: Paroxetine 47% The scenario describes a case of PTSD. |
Antidepressants (licenced indications)
The following table is intended as a guide to illustrate the specific licensed indications for the antidepressants (for adults). The table is consistent with both the Maudsley Guidelines and the British National Formulary.
Note: Of course they are all indicated in depression
| Indication | Antidepressants with this licence |
|---|---|
| Nocturnal enuresis in children | Amitriptyline, Imipramine, Nortriptyline |
| Phobic and obsessional states | Clomipramine |
| Adjunctive treatment of cataplexy associated with narcolepsy | Clomipramine |
| Panic disorder and agoraphobia | Citalopram, Escitalopram, Sertraline, Paroxetine, Venlafaxine |
| Social anxiety/ phobia | Escitalopram, Paroxetine, Sertraline, Moclobemide, Venlafaxine |
| Generalised anxiety disorder | Escitalopram, Paroxetine, Duloxetine, Venlafaxine |
| OCD | Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline |
| Bulimia nervosa | Fluoxetine |
| PTSD | Paroxetine, Sertraline |
