Which of the following medications is affected by moisture and so cannot be included in a compliance aid?
Drug stability
The stability of drugs varies considerably (Church 2006). Some medications cannot be included in compliance aids as they can be affected by their environment. Some drugs tend to absorb moisture from the air which renders them ineffective. Light is known to accelerate this process.
Examples of drugs effected this way and so unsuitable for compliance aids include:-
- Sodium valproate
- Zopiclone
- Venlafaxine
- Topiramate
- Methylphenidate
- Mirtazapine
- Olanzapine
- Amisulpride
- Aripiprazole
Church C (2006) How stable are medicines moved from original packs into compliance aids? The Pharmaceutical Journal Vol 276; 75-81.
