Serotonin receptors
Serotonin (5-hydroxytryptamine, 5-HT) receptors are mainly G protein receptors with the exception of 5-HT3 which is ligand gated.
Key facts to learn for the exam regarding 5-HT receptors include:-
Key facts to learn for the exam regarding 5-HT receptors include:-
- 5-HT3 is ligand gated
- 5-HT3 is most associated with nausea
- 5-HT7 is associated with circadian rhythms
- 5-HT2 stimulation is thought to underlie the effects of insomnia, agitation, and sexual dysfunction associated with SSRI use
