SSRI (bleeding)

December 09, 2018  AkraMania  

SSRI (bleeding)


SSRI's have been shown to increase the risk of bleeding, this probably results from platelets being deficient of serotonin due to the SSRIs effect on the transporter (serotonin is released by platelets and promotes vasoconstriction).

The risk of bleeding is elevated further in the following:-

  • Elderly
  • Those with a history of haemostatic defects
  • Patients on other drugs that elevate the risk (warfarin, NSAIDS, steroids)

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