Stevens-Johnson syndrome

Stevens-Johnson syndrome


Stevens-Johnson syndrome is a life threatening skin condition that can occur following medication use. The main culprits for this are the anticonvulsants (Levenson, 2010), particularly lamotrigine. It can also be caused by an infection.

It usually begins within the first few weeks of drug exposure, with fever, sore throat, and fatigue. Ulcers and other lesions begin to appear in the mucous membranes, almost always in the mouth and lips but also in the genital and anal regions. A rash of round lesions about an inch across arises on the face, trunk, arms and legs, and soles of the feet, but usually not the scalp.

Levenson L (2010) The American Psychiatric Publishing Textbook of Psychosomatic Medicine: Psychiatric Care of the Medically Lll p.683