Triptans
Triptans are specific 5-HT1 agonists used in the acute treatment of migraine. They are generally used first-line in combination therapy with an NSAID or paracetamol.
Prescribing points
Adverse effects
Contraindications
Prescribing points
- should be taken as soon as possible after the onset of headache, rather than at onset of aura
- oral, orodispersible, nasal spray and subcutaneous injections are available
Adverse effects
- 'triptan sensations' - tingling, heat, tightness (e.g. throat and chest), heaviness, pressure
Contraindications
- patients with a history of, or significant risk factors for, ischaemic heart disease or cerebrovascular disease
