Tuberous sclerosis
Tuberous sclerosis is a neurocutaneous syndrome associated with significant psychiatric co-morbidity including autism, ADHD, depression, anxiety, and even psychosis.
It shows autosomal dominant inheritance with complete penetrance and variable expression.
It is charcterised by the growth of multiple non-malignant tumours that grow in the brain and other vital organs.
It results from a mutation of one of two tumour suppression genes (TSC1 and TSC2).
It shows autosomal dominant inheritance with complete penetrance and variable expression.
It is charcterised by the growth of multiple non-malignant tumours that grow in the brain and other vital organs.
It results from a mutation of one of two tumour suppression genes (TSC1 and TSC2).
