White matter anatomy

White matter anatomy


The CNS is comprised of white and grey matter. The white matter is essentially cabling linking one part to another. In places these cables are aggregated to form distinct bundles.

There are three types of white matter cables as shown in the following table:

TractConnections
Projection tractsConnect higher centers of the brain (those beyond the brain stem) with lower centers (e.g. brainstem and spinal cord)
Commissural tractsConnect the two hemispheres together
Association tractsConnect regions of the same hemisphere. Long association connect separate lodes together whereas short association fibers connect separate gyri of the same lobe

You need to know some of the names for the different tracts, particularly what type of tract they are. The following tables gives the more common ones you need to know:

Tract typeExamplesDescription
ProjectionCorticospinalEfferent projection fibers that connect motor cortex to the brain stem and spinal cord
CorticobulbarEfferent projection fibers that connect motor cortex to the brain stem and spinal cord
Corona RadiataFibers to and from virtually all cortical areas fan out superolaterally from the internal capsule
Internal CapsuleMajor conduit of fibers to and from the cerebral cortex
Geniculocalcarine Tract (optic radiation)Connects the lateral geniculate nucleus to occipital (primary visual) cortex
CommissuralCorpus CallosumThe largest white matter fiber bundle, the corpus callosum is a massive accumulation of fibers connecting corresponding areas of cortex between the hemispheres
Anterior CommissureThe anterior commissure crosses through the lamina terminalis. Its anterior fibers connect the olfactory bulbs and nuclei; its posterior fibers connect middle and inferior temporal gyri
AssociationCingulumInterconnects portions of the frontal, parietal, and temporal lobes
Superior Occipitofrontal FasciculusConnects occipital and frontal lobes
Inferior Occipitofrontal FasciculusConnects the occipital and frontal lobes
Uncinate FasciculusConnects the orbital and inferior frontal gyri of the frontal lobe to the anterior temporal lobe
Superior Longitudinal (arcuate) FasciculusConnects the frontal lobe cortex to parietal, temporal, and occipital lobe cortices (the largest association bundle)
Inferior Longitudinal (occipitotemporal) FasciculusConnects temporal and occipital lobe cortices