Dementia (genetics)

Dementia (genetics)


The following genes have been implicated in dementia.

Form of dementiaGene(s) associated
Alzheimer'sPSEN1 (presenilin-1), PSEN2 (presenilin-2), APP (amyloid precursor protein), ApoE (apolipoprotein E)
Frontotemporal dementiaPGRN (progranulin), MAPT (tau)
Huntington's diseaseIT15 (huntingtin)
CADASIL*Notch3 (notch 3)

*CADSIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)