Dementia (genetics)
The following genes have been implicated in dementia.
*CADSIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)
Form of dementia | Gene(s) associated |
---|---|
Alzheimer's | PSEN1 (presenilin-1), PSEN2 (presenilin-2), APP (amyloid precursor protein), ApoE (apolipoprotein E) |
Frontotemporal dementia | PGRN (progranulin), MAPT (tau) |
Huntington's disease | IT15 (huntingtin) |
CADASIL* | Notch3 (notch 3) |
*CADSIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)