Concordance (Proband and pairwise)
Twin studies aim to establish the extent to which a disease/ condition is caused by genetic versus environmental factors.
Twin pairs are deemed concordant if both members of the pair are affected and discordant if only one is affected.
Concordance can either be pairwise or probandwise. The Pairwise concordance rate is the proportion of twin pairs in which both twin have the disease. The probandwise concordance rate is the proportion of proband twins who have an affected co-twin
Twin pairs are deemed concordant if both members of the pair are affected and discordant if only one is affected.
Concordance can either be pairwise or probandwise. The Pairwise concordance rate is the proportion of twin pairs in which both twin have the disease. The probandwise concordance rate is the proportion of proband twins who have an affected co-twin
